Experimental Medicine extended the lives of mice
Into old age young, healthy and full of energy, a dream of mankind, is, so far, only a utopia. This could change in the future, because recent research dealing with treatments that can slow down the aging process and perhaps even stop. In a recent study, Researchers were able to extend the life span of mice by slowed down by a new drug the aging process.
A research team from the Weizmann Institute of Science in Israel decrypted recently, the manner in which the immune system is on the aging process involved. According to the study, increasingly vergreiste cells in the body, burden the immune system with increasing age. These cells are restricted in their function or irreparable damage. Through a newly developed drug, the researchers were able to slow down the process of cell ageing in mice, increasing their life span increased. The results of the study were recently published in the renowned scientific journal “Nature Communications”.
As our immune system ages
The Team led by Professor Valery Krizhanovsky, and Dr. Yossi Ovadya describes how vergreis prepare cells of our immune system with age problems. The so-called senescent cells are cells that are not yet dead, but in their functioning, severely restricted or damaged. The older we get, the more vergreiste cells in our body in the circulation. According to the research team, these cells are significantly involved in inflammatory processes, the typical old-age disease.
The expiration of the study
In one Experiment, the researchers used the ends of genetically modified mice that aged prematurely. These mice suffered more quickly to chronic inflammation and a reduced capacity to work, as normal mice of the same age. Also, these mice looked get old faster and died earlier.
Cell aging can be slow down
In their studies, the scientists found scientists that cellular aging can be slow down by inhibiting certain proteins. The Team administered ABT the prematurely ageing mice, the drug-737, the proteins are suppressed, which have been associated with the aging process. Then, the mice were more active and their life span is increased.
Healthier, more active and longer-lasting
As the research showed, did the animals exceptionally well to the drug. Your blood as well as activity tests showed an improvement and their fabric resembled that of young mice. The Team was also able to show that in the case of the treated mice both significantly less vergreiste cells as well as inflammatory processes.
May also work in humans?
The researchers see in their findings in fact, a way to an Anti-Aging therapy for people develop. The Team now wants to investigate in further studies how the human immune system can encourage the increase in the Firat to dispose of cells faster. If your theories prove to be true, it might soon be a pill against aging. (vb)